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Bato M. KoraŠ, Ph.D.

associate professor
Faculty of Biology, Studentski trg 3, Beograd

Phone:   011-2078307

E-mail:   koracb AT ibiss · bg · ac · rs

Personal data

Education: B.Sc. 1988 Faculty of Science (Molecular Biology and Physiology), University of Belgrade, Serbia; M.Sc. 1991 Faculty of Science (Molecular Biology and Physiology), University of Belgrade, Serbia; Ph.D. 1996 Faculty of Science (Molecular Biology and Physiology), University of Belgrade, Serbia.

Education and qualifications

1988: Undergraduate studies - Biology / University of Belgrade - Faculty of Biology (Belgrade, Serbia)

1991: Master of science studies - Biology / University of Belgrade - Faculty of Biology (Belgrade, Serbia)

1996: Doctoral academic (PhD) studies - Biology / University of Belgrade - Faculty of Biology (Belgrade, Serbia)

History of employment

2004: Associate professor / University of Belgrade - Faculty of Biology (Belgrade, Serbia)

Scientific interest

Molecular biology, biochemistry and physiology, with the special focus on the role of redox regulation of fundamental cellular processes (proliferation, hyperplasia, angiogenesis, mitochondriogenesis) in pathological and physiological states, as well as during adaptation to specific environmental conditions (hibernation). The central interest is investigation of mechanisms of action of reactive oxygen and nitrogen species, by focusing research on redox-sensitive molecules and processes, and redox sensitive transcription factors, especially in terms of possibilities for changing the cellular redox status for therapeutic use in a treatment of severe metabolic disorders, metabolic syndrome, obesity, diabetes, cardiovascular and neurodegenerative diseases and male infertility.

Other activities

Member of Society for Free Radical Research - Europe.

Member of Federation of European Neuroscience Societies (FENS).

Member of Serbian Society for Mitochondrial and Free Radical Physiology. President and co-founder of the Society

Member of Serbian Neuroscience Society.

Member of Physiological Society.

Member of Serbian Nutrition Society.

Member of Serbian Laboratory Animal Science Association (SLASA). President of the Ethics Committee of the Association

Member of European Association for the Study of Diabetes..

History of employment: 2007- Principal Scientist, University of Belgrade, Institute for Biological                       Research, Belgrade, Serbia; 2009- Associate professor, University of Belgrade, Faculty of Biology, Belgrade, Serbia.
National research projects:   - White and/or brown: the importance of adipose tissue in maintaining the overall redox dependent metabolic control of physiological and metabolic adaptations. - The role of reactive oxygen and nitrogen species in reproduction: possible application in the treatment of human infertility.

Educational activities

Representative references

20 selected publications:

 

1. Jankovic A, Korac A, Srdic-Galic B, Buzadzic B, Otasevic V, Stancic A, Vucetic M, Markelic M, Velickovic K, Golic I, and Korac B. (2014) Differences in the redox status of human visceral and subcutaneous adipose tissues - relationships to obesity and metabolic risk. Metabolism: Clinical and Experimental, 63: 661-671.

 

2. Buzadzic B, Vucetic M, Jankovic A, Stancic A, Korac A, Korac B, and Otasevic V. (2014) New insights into male (in)fertility: The importance of NO. Br. J. Pharmacol., doi: 10.1111/bph.12675.

 

3. Otasevic V, Surlan L, Vucetic M, Tulic I, Buzadzic B, Stancic A, Jankovic A, Velickovic K, Golic I, Markelic M, Korac A, and Korac B. (2014)  Different expression patterns of mitochondrial OXPHOS components and mitofusin 1/dynamin related protein 1 is associated with human embryo fragmentation. Reproduction, Fertility and Development, http://dx.doi.org/10.1071/RD13415.

 

4. Velickovic K, Cvoro A, Srdic B, Stokic E, Markelic M, Golic I, Otasevic V, Stancic A, Jankovic A, Vucetic M, Buzadzic B, Korac B, and Korac A. (2014) Expression and Subcellular Localization of Estrogen Receptors α and β in Human Fetal Brown Adipose Tissue. J Clin Endocrinol Metab., 99: 151-159.

 

5. Vučetić M., Stančić A., Otašević V., Janković A., Korać A., Markelić M., Veličković K., Golić I., Buzadžić B., Storey B.K. and Korać B. (2013) The impact of cold acclimation and hibernation on antioxidant defenses in the ground squirrel (Spermophilus citellus): An update. Free Radic. Biol. Med., 65: 916-924.

 

6. Jankovic A, Korac A, Buzadzic B, Otasevic V, Stancic A, Vucetic M, Markelic M, Velickovic K, Golic I, and Korac B. (2013) Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation. J. Obes., http://dx.doi.org/10.1155/2013/937572.

 

7. Stančić A, Otašević V, Janković A, Vučetić M, Ivanović-Burmazović I, Filipović RM, Korać A, Markelić M, Veličković K, Golić I, Buzadžić B, and Korać B. (2013) Molecular basis of hippocampal energy metabolism in diabetic rats: The effects of SOD mimic. Brain Res Bull., 99: 27-33.

 

8. Otašević V., Korać A., Vučetić M., Macanović B., Garalejić E., Ivanović-Burmazović I., Filipović MR., Buzadžić B., Stančić A., Janković A., Veličković K., Golić I., Markelić M. and Korać B. (2013) Is Manganese (II) Pentaazamacrocyclic Superoxide Dismutase Mimic Beneficial for Human Sperm Mitochondria Function and Motility? Antioxid. Redox Signal., 18: 170-178.

 

9. Velickovic K, Markelic M, Golic I, Otasevic V, Stancic A, Jankovic A, Vucetic M, Buzadzic B, Korac B, and Korac A. (2013) Long-term dietary L-arginine supplementation increases endothelial nitric oxide synthase and vasoactive intestinal peptide immunoexpression in rat small intestine. Eur. J. Nutr., doi:10.1007/s00394-013-0585-8.

 

10. Stancic A, Buzadzic B, Korac A, Otasevic V, Jankovic A, Vucetic M, Markelic M, Velickovic K, Golic I, and Korać B. (2013) Regulatory role of PGC-1 alpha/PPAR signaling in skeletal muscle metabolic recruitment during cold acclimation. J Exp. Biol., 216: 4233-4241.

 

11. Stančić A., Korać A., Buzadžić B., Otašević V., Janković A., Vučetić M. and Korać B. (2012) L-Arginine in Nutrition: Multiple Beneficial Effects in the Etiopathology of Diabetes. J. Nutritional Therapeutics, 1: 114-131.

 

12. Jović M., Stančić A., Nenadić D., Cekić O., Nezić D., Milojević P., Micović S., Buzadžić B., Korać A., Otašević V., Janković A., Vučetić M., Veličković K., Golić I. and Korać B. (2012) Mitochondrial molecular basis of sevoflurane and propofol cardioprotection in patients undergoing aortic valve replacement with cardiopulmonary bypass. Cell. Physiol. Biochem., 29: 131-142.

 

13. Vučetić M., Otašević V., Korać A., Stančić A., Janković A., Markelić M., Golić I., Veličković K., Buzadžić B. and Korać B. (2011) Interscapular brown adipose tissue metabolic reprogramming during cold acclimation: Interplay of HIF-1α and AMPKα. Biochim. Biophys. Acta, 1810:1252-1261.

 

14. Otašević V., Korać A., Buzadžić B., Stančić A., Janković A. and Korać B. (2011) Nitric oxide and thermogenesis - challenge in molecular cell physiology. Frontiers Biosci., 3: 1180-1195.

 

15. Petrović V., Buzadžić B., Korać A., Vasilijević A., Janković A. and Korać B. (2010) NO modulates the molecular basis of rat interscapular brown adipose tissue thermogenesis. Comp. Biochem. Physiol. C, 152: 147-159.

 

16. Petrović V., Buzadžić B., Korać A., Vasilijević A., Janković A. and Korać B. (2009) L-arginine supplementation induces glutathione synthesis in interscapular brown adipose tissue through activation of glutamate-cysteine ligase expression: The role of nitric oxide. Chem. Biol. Interact., 182: 204-212.

 

17. Korać A., Buzadžić B., Petrović V., Vasilijević A., Janković A. and Korać B. (2008). The role of nitric oxide in remodeling of capillary network in rat interscapular brown adipose tissue after long-term cold acclimation. Histol. Histopathol., 23, 441-450.

 

18. Petrović V., Korać A., Buzadžić B., Vasilijević A., Janković A., Mićunović K. and Korać B. (2008). Nitric oxide regulates mitochondrial re-modeling in interscapular brown adipose tissue: ultrastructural and morphometric-stereologic studies. J. Microsc., 232, 542-548.

 

19. Vasilijević A., Buzadžić B., Korać A., Petrović V., Janković A. and Korać B. (2007). Beneficial effects of L-arginine-nitric oxide-producing pathway in rats treated with alloxan. J. Physiol., 584, 921-933.

 

20. Petrović V., Buzadžić B., Korać A., Vasilijević A., Janković A. and Korać B. (2006). Free radical equilibrium in interscapular brown adipose tissue: relationship between metabolic profile and antioxidative defense. Comp. Biochem. Physiol. C, 142, 60-65.

 

Thu Nov 28 12:05:04 2019

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