Faculty of Chemistry, Studentski trg 12-16, Beograd
Department of Biochemistry
Phone: 011-3336657
Phone (local): 657
Laboratory: 249a
E-mail: sminic@chem.bg.ac.rs
Personal data
Born on November 25, 1989 in Nikšić, Montenegro. Speaks Serbian and English language.
Education and qualifications
2008-2012: Basic academic (BSc) studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
2012-2013: Master academic (MSc) studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
2013-2017: Doctoral academic (PhD) studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
History of employment
2017-2018: Graduate researcher / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
2018-2021: Scientific associate / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
2021-2023: Assistant with phd / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
2022: Senior scientific associate / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
2023: Assistant professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
Scientific interest
Bioactive (chromo)peptides from algae
Protein-ligand interactions in food systems
Protein stability at high-pressure conditions
Development of algal-based products as cell media components for meat cultivation
Awards and merits
2008: First prize, National Chemistry Competition of Montenegro for High School Students
2013: Diploma "Djordje Stefanovic", awarded by the Faculty of Chemistry to the best student in generation of study group Biochemistry
2013: University of Belgrade Award as the best student of the Faculty of Chemistry for 2011/2012 school year.
2013: Serbian Chemical Society annual award
2013: Award as one of the top five students in the municipality of Nikšić
2015: FEBS grant to attend Young Scientist Forum and 40th FEBS Congress in Berlin
2022: FEBS short term fellowship
Other activities
Member of Serbian Chemical Society from 2013.
Member of Serbian Biochemical Society from 2014.
Member of Serbian Proteomics Association from 2015.
Member of the Committee for Exams Recognition from February 8, 2024.
Educational activities
- Regulation of Biochemical Processes (403B2)
- Enzymology (431B2)
- Biochemistry of Food and Nutrition (432B2)
- Mechanisms of Action of Physiologically Active Compounds (454B2)
Participation in research projects
Active projects:
- 2021-2025: An Innovative Analytical Platform to Investigate the Effect and Toxicity of Micro and Nano Plastics Combined with Environmental Contaminants on the Risk of Allergic Disease in Preclinical and Clinical Studies (IMPTOX) – 965173
project type: Horizon 2020
project is funded by: European Commission (Brusseles, Belgium) - 2022-2024: Strengthening the potential of algal proteins for food colouring and fortification using high-pressure technology (PRESSION) – ANSO-CR-PP-2021-01 (principal investigator)
project type: International Research Projects
project is funded by: Alliance of International Science Organizations (Peking, China) - 2023-2025: Comprehensive platform for selecting and producing algal extracts as cell media components for meat cultivation. (ALG2MEAT) (principal investigator)
project type: International Research Projects
project is funded by: Good Food Institute (Delaver, United States) - 2024-2026: Exploring the potential of algal-derived (chromo)peptides as serum replacement components for meat cultivation (Pep4Meat) (principal investigator)
project type: PROMIS
project is funded by: Science Fund of the Republic of Serbia (Belgrade, Serbia)
Finished projects:
- 2018: Twinning of research activities for the frontier research in the fields of food, nutrition and environmental 'omics (FoodEnTwin) – No. 810752
project type: Horizon 2020
project is funded by: European Commission (Brusseles, Belgium)
Representative references
Poglavlja u knjigama/book chapters:
Nikolić Milan; Minić Simeon; Mačvanin Mirjana; Stanić-Vučinić Dragana; Ćirković Veličković Tanja. Analytical Protocols in Phycobiliproteins Analysis. Pigments from Microalgae (2020). Eduardo Jacob-Lopes, Maria Isabel Queiroz, Leila Queiroz Zepka (Eds.), Springer. ISBN 978-3-030-50970-5.
Stanić-Vučinić Dragana; Minić Simeon; Nikolić Milan; Ćirković Veličković Tanja. Spirulina phycobiliproteins as food components and complements. Microalgal Biotechnology (2018). Eduardo Jacob-Lopes (Ed.), InTech Open Access Publisher. ISBN 978-953-51-6024-3.Ćirković Veličković Tanja; Stanić-Vučinić Dragana; Al-Hanis Ayah; Mihailović Jelena; Prodić Ivana; Minić Simeon; Stojadinović Marija; Radibratović Milica, Milčić Miloš. Delivery of Epigalocatechin-3-Gallate by Bovine Alpha-Lactalbumin Based on Their Non-covalent Interactions. Encyclopedia of Food Chemistry (2018). Laurence Melton, Peter Varelis, Fereidoon Shahidi (Eds.), Elsevier. ISBN 978-012814045-1.
Izabrani radovi/peer-reviewed journal articles:
Minić, S., Annighofer, B., Hélary, A., Sago L., Cornu, D., Brûlet, B., Combet, S. (2022) Structure of proteins under pressure: covalent binding effects of biliverdin on beta-lactoglobulin, Biophysical Journal, 121, 1-12.
Simović, A., Combet, S., Ćirković Veličković, T., Nikolić, M. R., and Minić, S.L. (2022). Probing the stability of the food colourant R-phycoerythrin from dried Nori flakes. Food chemistry, 374, 1-10
Radomirović, M., Minić, S., Stanić-Vučinić, D., Nikolić, M., Van Haute, S., Rajković, A., and Ćirković Velicković, T. (2022). Phycocyanobilin-modified β-lactoglobulin exhibits increased antioxidant properties and stability to digestion and heating. Food Hydrocolloids, 123, 1-10.
Gligorijević, N., Šukalović, V., Minić, S.L., Miljuš, G., Nedić, O and Penezić, A. (2021). Physicochemical characterisation of dihydro-alpha-lipoic acid interaction with human serum albumin by multi-spectroscopic and molecular modelling approaches. Journal of the Serbian Chemical Society, 86 (9) 795–807.
Gligorijević, N., Minić, S.L., Radibratović, M., Papadimitriou, V., Nedić, O., Sotiroudis, T.G., Nikolić, M.R. (2021). Nutraceutical phycocyanobilin binding to catalase protects the pigment from oxidation without affecting catalytic activity. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 251, 1-9.
Minić, S.L., Annighöfer, B., Hélary, A., Hamdane, D., Hui Bon Hoa, G., Loupiac, C., Brûlet, A., and Combet, S. (2020). Effect of Ligands on HP-Induced Unfolding and Oligomerization of β-Lactoglobulin. Biophysical journal, 119, 2262-2274.Gligorijević, N., Minić, S., Robajac, D., Nikolić, M., Ćirković Veličković, T., and Nedić O. (2019). Characterisation and the effects of bilirubin binding to human fibrinogen. International Journal of Biological Macromolecules, 128, 74-79.
Radibratović M., Al-Hanish A., Minić S.L., Radomirović M., Milčić M., Stanić-Vučinić D., Tanja Ćirković Veličković. (2019). Stabilisation of apo α-lactalbumin by binding of epi-gallocatechin-3-gallate: experimental and molecular dynamics study. Food chemistry, 278, 388-395.
Minić, S.L., Radomirović, M., Savković, N., Radibratovič, M., Mihailović, J., Vasović, T., Nikolić, M., Milčić, M., Stanić-Vučinić, D., Ćirković Veličković, T. (2018). Covalent binding of food-derived blue pigment phycocyanobilin to bovine β-lactoglobulin under physiological conditions. Food chemistry, 269, 43-52.
Gligorijević, N., Minić, S.L., Križáková M., Katrlík., J., and Nedić, O. Structural changes of fibrinogen as a consequence of cirrhosis. (2018). Thrombosis Research, 166, 43-49.
Minić, S.L., Ješić, M., Đurović, D., Miletić, S., Lugonja, N., Marinković, V., Nikolić-Kokić, A., Spasić, S., Vrvić, M.M. (2018). Redox properties of transitional milk from mothers of preterm infants. Journal of Paediatrics and Child Health, 54(2), 160-164.
Minić, S.L., Stanić-Vučinić, D., Radomirović, M., Radibratović, M., Milčić, M., Nikolić, M.R, Ćirković Veličković, T. (2018). Characterisation and effects of binding of food-derived bioactive phycocyanobilin to bovine serum albumin. Food Chemistry, 239, 1090-1099.
Peruško, M., Al-Hanish, A., Mihailović, J., Minić, S.L., Trifunović, S., Prodić, I., Ćirkovic Veličković, T. (2017). Antioxidative capacity and binding affinity of the complex of green tea catechin and beta-lactoglobulin glycated by the Maillard reaction. Food Chemistry, 232, 744-752.
Radibratović, M., Minić, S.L.*, Stanić-Vučinić, D., Nikolić, M., Milčić, M., Ćirković Veličković, T. (2016). Stabilisation of Human Serum Albumin by the Binding of Phycocyanobilin, a Bioactive Chromophore of Blue-Green Alga Spirulina: Molecular Dynamics and Experimental Study. PLoS One, 11(12), e0167973. *co-first author
Al-Hanish, A., Stanić-Vučinić, D., Mihailović, J., Prodić, I., Minić, S.L, Stojadinović, M., Radibratović, M., Milčić, M., Ćirković Veličković, Tanja. (2016). Noncovalent interactions of bovine α-lactalbumin with green tea polyphenol, epigalocatechin-3-gallate. Food Hydrocolloids, 61, 241-250.
Minić S.L., Stanić-Vučinić D., Krstić M., Vesić J., Nikolić M., Ćirković Veličković T. (2016). Digestion by pepsin releases biologically active chromopeptides from C-phycocyanin, a blue-colored biliprotein of microalga Spirulina. Journal of Proteomics, 147, 132-139.
Minić, S.L., Milčić, M., Stanić-Vučinić, D., Radibratović, M., Sotiroudis, T.G., Nikolić, M.R., Ćirković Veličković, T. (2015). Phycocyanobilin, a bioactive tetrapyrrolic compound of blue-green alga Spirulina, binds with high affinity and competes with bilirubin for binding on human serum albumin. RSC Advances, 5(76), 61787-61798.