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Igor M. Opsenica, Ph.D.

associate professor
Faculty of Chemistry, Studentski trg 12-16, Beograd
Department of Organic Chemistry

Phone:   011-3336684

Phone (local):   684

Office:   482

Laboratory:   524

E-mail:   igorop AT chem · bg · ac · rs

Personal data

Born on July 30, 1977 in Belgrade, Serbia. Married. Speaks Serbian and English language.

Education and qualifications

2003: Undergraduate studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2007: Master of science studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2011: Doctoral academic (PhD) studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

History of employment

2007: Teaching assistant / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2008-2012: Assistant / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2012-2017: Assistant professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2017: Associate professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

Scientific interest

Organic chemistry, medicinal chemistry, chemistry of heterocyclic compounds.

Other activities

Member of Serbian Chemical Society from 2003 - Section for organic chemistry; Section for medicinal chemistry. Member of the administrative committee.

Member of American Chemical Society from 2006 - Section for organic chemistry.

Educational activities

Projects

Author identification numbers

Representative references

Knjige i revijalni radovi / Books and reviews:

Izabrani radovi / Selected papers:

  1. V. Ajdačić, S. Stepanović, M. Zlatović, M. Gruden, I. M. Opsenica, Decarbonylative dibromination of 5-phenylthiophene-2-carbaldehyde with bromine, Synthesis, 2016, 48, 4423-4430.
  2. N. Božinović, S. Šegan, S. Vojnovic, A. Pavic, B. A. Šolaja, J. Nikodinovic-Runic, I. M. Opsenica, Synthesis and anti-Candida activity of novel benzothiepino[3,2-c]pyridine derivatives, Chem. Biol. Drug Des., 2016, 88, 795-806.
  3. N. Božinović, B. A. Šolaja, I. M. Opsenica, Microwave-assisted synthesis of azepines via nucleophilic aromatic substitution, J. Serb. Chem. Soc., 2016, 81, 1225-1230.
  4. V. Ajdačić, L. Senerovic, M. Vranić, M. Pekmezovic, V. Arsic-Arsenijevic, A. Veselinovic, J. Veselinovic, B. A. Šolaja, J. Nikodinovic-Runic, I. M. Opsenica, Synthesis and evaluation of thiophene-based guanylhydrazones (iminoguanidines) efficient against panel of voriconazole-resistant fungal isolates, Bioorg. Med. Chem., 2016, 24, 1277-1291.
  5. S. Šegan, I. Opsenica, M. Zlatović, D. Milojković-Opsenica, B. Šolaja, Quantitative structure retention/activity relationships of biologically relevant 4-amino-7-chloroquinoline based compounds, J. Chromatogr. B, 2016, 1012, 144-152.
  6. I. M. Opsenica, T. Ž. Verbić, M. Tot, R. J. Sciotti, B. S. Pybus, O. Djurković-Djaković, K. Slavić, B. A. Šolaja, Investigation into novel thiophene- and furan-based 4-amino-7-chloroquinolines afforded antimalarials that cure mice, Bioorg. Med. Chem., 2015, 23, 2176-2186.
  7. N. Božinović, I. Novaković, S. Kostić-Rajačić, I. M. Opsenica, B. A. Šolaja, Synthesis and antimicrobial activity of azepine and thiepine derivatives, J. Serb. Chem. Soc., 2015, 80, 839-852.
  8. I. M. Opsenica, M. Tot, L. Gomba, J. E. Nuss, R. J. Sciotti, S. Bavari, J. C. Burnett, B. A. Šolaja, 4-Amino-7-chloroquinolines: Probing Ligand Efficiency Provides Botulinum Neurotoxin Serotype A Light Chain Inhibitors with Significant Antiprotozoal Activity, J. Med. Chem., 2013, 56, 5860-5871.
  9. N. Božinović, I. Opsenica, B. A. Šolaja, Double Palladium-Catalyzed Synthesis of Azepines, Synlett, 2013, 24, 49-52.
  10. I. Opsenica, V. Filipović, J. E. Nuss, L. M. Gomba, D. Opsenica, J. C. Burnett, R. Gussio, B. A. Šolaja, S. Bavari, The syntheses of 2,5-Bis(4-amidinophenyl)thiophene derivatives providing nM-range inhibition of the botulinum neurotoxin serotype A metalloprotease, Eur. J. Med. Chem., 2012, 53, 374-379.
  11. I. Opsenica, J. C. Burnett, R. Gussio, D. Opsenica, N. Todorović, C. A. Lanteri, R. J. Sciotti, M. Gettayacamin, N. Basilico, D. Taramelli, J. E. Nuss, L. Wanner, R. G. Panchal, B. A. Šolaja, S. Bavari, A Chemotype That Inhibits Three Unrelated Pathogenic Targets: The Botulinum Neurotoxin Serotype A Light Chain, P. falciparum Malaria, and the Ebola Filovirus, J. Med. Chem., 2011, 54, 1157-1169.
  12. I. N. Cvijetić, Ž. P. Žižak, T. P. Stanojković, Z. D. Juranić, N. Terzić, I. M. Opsenica, D. M. Opsenica, I. O. Juranić, B. J. Drakulić, An alignment independent 3D QSAR study of the antiproliferative activity of 1,2,4,5-tetraoxanes, Eur. J. Med. Chem., 2010, 45, 4570-4577.
  13. I. M. Opsenica, K. K. Smith, L. Gerena, S. Gaica, B. A. Šolaja, Ribofuranose as a carrier of tetraoxane and 4-aminoquinoline antimalarial pharmacophores, J. Serb. Chem. Soc., 2008, 73, 1021-1025.
  14. I. Opsenica, D. Opsenica, C. A. Lanteri, L. Anova, W. K. Milhous, K. S. Smith, B. A. Šolaja: New Chimeric Antimalarials with 4-Aminoquinoline Moiety Linked to a Tetraoxane Skeleton, J. Med. Chem., 2008, 51, 6216-6219.
  15. B. A. Šolaja, D. Opsenica, K. S. Smith, W. K. Milhous, N. Terzić, I. Opsenica, J. C. Burnett, J. Nuss, R. Gussio, S. Bavari: Novel 4-Aminoquinolines Active against Chloroquine-Resistant and Sensitive P. falciparum Strains that also Inhibit Botulinum Serotype A, J. Med. Chem., 2008, 51, 4388-4391.
  16. I. Opsenica, D. Opsenica, K. S. Smith, W. K. Milhous, B. A. Šolaja: Chemical Stability of the Peroxide Bond Enables Diversified Synthesis of Potent Tetraoxane Antimalarials, J. Med. Chem., 2008, 51, 2261-2266.
  17. I. Opsenica, D. Opsenica, K. Smith, W. K. Milhous, M. Stratakis, B. Šolaja: On peroxide antimalarials, J. Serb. Chem. Soc., 2007, 72, 1181-1190.
  18. E. Hatzakis, I. Opsenica, B. A. Solaja, M. Stratakis: Synthesis of novel polar derivatives of the antimalarial endoperoxides ascaridole and dihydroascaridole, Arkivoc, 2007, viii, 124-135.
  19. I. Opsenica, N. Terzić, D. Opsenica, G. Angelovski, M. Lehnig, P. Eilbracht, B. Tinant, Z. Juranić, K. S. Smith, Y. S. Yang, D. S. Diaz, P. L. Smith, W. K. Milhous, D. Đoković, and B. A. Šolaja: Tetraoxane Antimalarials and Their Reaction with Fe(II), J. Med. Chem., 2006, 49, 3790-3799.
  20. I. Opsenica, N. Terzić, D. Opsenica, W. K. Milhous, B. Šolaja: 7,8,15,16-Tetraoxa-dispiro[5.2.5.2]hexadecane-3-carboxylic acid derivatives and their antimalarial activity, J. Serb. Chem. Soc., 2004, 69, 919-922.

Mon Dec 11 12:54:53 2017

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