Course code:
2152H		 Course name:
Bioinorganic Chemistry

Academic year:

2012/2013.

Attendance requirements:

There are no requirements.

ECTS:

8

Study level:

graduate academic studies

Study program:

Chemistry: 1. year, winter semester, elective (2IP2H) course

Teacher:

Gordana N. Vučković, Ph.D.

Assistant:

Aleksandar R. Savić, Ph.D.
assistant professor, Faculty of Chemistry, Studentski trg 12-16, Beograd

Hours of instruction:

Weekly: three hours of lectures + two hours of exercises + three hours of labwork (3+2+3)

Goals:

Introduce students to the basic bioinorganic chemistry, methods applied, corresponding literature, especially new scientific papers.

Outcome:

After this course the student would be able to understand the possible practical application of the knowledge from this discipline in medicine, pharmacy, diet, environmental protection and in own scientific work.

Teaching methods:

Interactive,classical, consultative teaching, semester paper, experimental and theoretical work.

Extracurricular activities:

Visits to the relevant institutions, lectures of the visiting scientists, writing of semester papers, homework.

Coursebooks:

Main coursebooks:

  • K. B. Jacimirskij, Introduction to bioinorganic chemistry, translated from Russian, Privredni pregled, Belgrade, 1980.
  • H. B. Bertini, S. J. Lippard, Principles in Bioinorganic Chemistry, University Science Book, 1994.
  • Authorized lectures, G.Vuckovic

Supplementary coursebooks:

  • J. A. Cowan, Inorganic Biochemistry, An introduction, 2nd ed; Wiley-VCH; New York 1997.
  • Rosete M Roat-Malone, Bioinorganic chemistry, short course,2nd ed. Wiley-Interscience, New Jersey 2007, an electronic version

Additional material:

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  Course activities and grading method

Lectures:

10 points (3 hours a week)

Syllabus:

1. IntrŢduction to bioinorganic chemistry.

2. Methods for the investigations of biocomplexes (for each of them advantages and limitations will be discuss).

3. Bioligands and interactions with biometals.

4-6. Distribution of bioelements in human and other organisms and their importance. Biometals.

7-9. Metaloenzymes as catalysts for hydrolytic and reduction reactions.Oxygen carriers.

10. Model systems and probes. Blood alternatives.

11. Nitrogen fixation and cycle.

12. Toxic elements, inhibition and eliminations from organism and environment.

13-15. Application of metals and their compounds in catalysis, medicine, pharmacy, diet and environmental protection.

Exercises:

10 points (2 hours a week)

Labwork:

10 points (3 hours a week)

Semester papers:

20 points

Colloquia:

10 points

Written exam:

40 points